Radiation Response Modified by Degradable Starch Microspheres: Experiments On The Rat's Foot
| Autor: | B. Larsson, B. Jung, J. O. Forsberg |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Male
medicine.medical_specialty Radiation Dosage Radiation Protection medicine Animals Irradiation Hypoxia Radiation Injuries Skin Degradable starch microspheres Foot Chemistry Dose-Response Relationship Radiation Starch General Medicine Hypoxia (medical) Microspheres Rats Surgery Skin reaction Radiodermatitis medicine.symptom Radiation response Hair Biomedical engineering |
| Zdroj: | Acta Radiologica: Oncology, Radiation, Physics, Biology. 17:199-208 |
| ISSN: | 0348-5196 |
| DOI: | 10.3109/02841867809127921 |
| Popis: | Skin reaction in the rat's foot was used as an experimental method to evaluate the protective potential of profound temporary hypoxia against roentgen radiation produced by a linear accelerator. Hypoxia was induced by intraarterial injection of degradable starch microspheres. The irradiation dose needed to evoke a certain reaction in the hypoxic feet was 2.0 times the dose giving the same reaction in a control group. The results point towards a new technique of inducing local hypoxia in healthy tissues which need to be protected in an irradiation field. |
| Databáze: | OpenAIRE |
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