Excess mortality among people with podoconiosis: secondary analysis of two Ethiopian cohorts
| Autor: | Christopher I. Jones, James A. Berkley, Hannah Masraf, Gail Davey, Abreham Tamiru, Temesgen Azemeraw, Trudie Lang, Stephen Bremner, Esther Kivaya, Melanie J. Newport, Abebe Kelemework, Greg Fegan, Moses Ngari, Meseret Molla |
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| Rok vydání: | 2020 |
| Předmět: |
030231 tropical medicine
Population 03 medical and health sciences 0302 clinical medicine Secondary analysis Humans Medicine AcademicSubjects/MED00860 Elephantiasis 030212 general & internal medicine Podoconiosis education Excess mortality podoconiosis education.field_of_study Special Issue business.industry Mortality rate Public Health Environmental and Occupational Health Secondary data General Medicine medicine.disease mortality non-filarial elephantiasis Confidence interval AcademicSubjects/MED00290 Infectious Diseases Cohort Original Article Parasitology Ethiopia business Demography |
| Zdroj: | Transactions of the Royal Society of Tropical Medicine and Hygiene |
| ISSN: | 1878-3503 0035-9203 |
| DOI: | 10.1093/trstmh/traa150 |
| Popis: | Background While morbidity attributable to podoconiosis is relatively well studied, its pattern of mortality has not been established. Methods We compared the age-standardised mortality ratios (SMRs) of two datasets from northern Ethiopia: podoconiosis patients enrolled in a 1-y trial and a Health and Demographic Surveillance System cohort. Results The annual crude mortality rate per 1000 population for podoconiosis patients was 28.7 (95% confidence interval [CI] 17.3 to 44.8; n=663) while that of the general population was 2.8 (95% CI 2.3 to 3.4; n=44 095). The overall SMR for the study period was 6.0 (95% CI 3.6 to 9.4). Conclusions Podoconiosis patients experience elevated mortality compared with the general population and further research is required to understand the reasons. |
| Databáze: | OpenAIRE |
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