A dispersive liquid-liquid microextraction based on solidification of floating organic droplet followed by injector port silylation coupled with gas chromatography–tandem mass spectrometry for the determination of nine bisphenols in bottled carbonated beverages
| Autor: | G.N.V. Satyanarayana, Kapil Mandrah, Somendu Kumar Roy |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Bisphenol A
Chromatography Gas Liquid Phase Microextraction Bisphenol Analytical chemistry Carbonated Beverages 010501 environmental sciences 01 natural sciences Biochemistry Bisphenol AF Analytical Chemistry chemistry.chemical_compound Phenols Cyclohexanes Limit of Detection Tandem Mass Spectrometry Sulfones Benzhydryl Compounds Derivatization 0105 earth and related environmental sciences Detection limit Chromatography Gas Chromatography/Tandem Mass Spectrometry 010401 analytical chemistry Organic Chemistry Injection port General Medicine 0104 chemical sciences Bisphenol S chemistry Solvents Food Analysis |
| Zdroj: | Journal of Chromatography A. 1528:10-17 |
| ISSN: | 0021-9673 |
| DOI: | 10.1016/j.chroma.2017.10.071 |
| Popis: | In the present study, a method has been efficiently developed for the first time to determine nine bisphenol analogues [bisphenol A (BPA), bisphenol C (BPC), bisphenol AF (BPAF), bisphenol E (BPE), bisphenol F (BPF), bisphenol G (BPG), bisphenol M (BPM), bisphenol S (BPS), and bisphenol Z (BPZ)] together in bottled carbonated beverages (collected from the local market of Lucknow, India) using dispersive liquid-liquid microextraction process. This is based on solidification of floating organic droplet (DLLME-SFO) followed by injector port silylation coupled with gas chromatography-tandem mass spectrometry. The process investigated parameters of DLLME-SFO (including the type of extraction and disperser solvents with their volumes, effect of pH, ionic strength, and the sample volume), factors influencing to injection port derivatization like, collision energy, injector port temperature, derivatizing reagent with sample injection volume, and type of organic solvent. BPA, BPF, BPZ, and BPS were detected in each sample; whereas, other bisphenols were also detected in some carbonated beverage samples. After optimizing the required conditions, good linearity of analytes was achieved in the range of 0.097-100ngmL-1 with coefficients of determination (R2)≥0.995. Intra-day and inter day precision of the method was good, with relative standard deviation (% RSD)≤10.95%. The limits of detection (LOD) and limits of quantification (LOQ) values of all bisphenols were ranged from 0.021 to 0.104ngmL-1 and 0.070 to 0.343ngmL-1, respectively. The recovery of extraction was good (73.15-95.08%) in carbonated beverage samples and good enrichment factors (96.36-117.33) were found. Thus, the developed method of microextraction was highly precise, fast, and reproducible to determine the level of contaminants in bottled carbonated beverages. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect