In-line balanced detection stimulated Raman scattering microscopy
| Autor: | Francesco Crisafi, Marco Marangoni, Giulio Cerullo, Dario Polli, Vikas Kumar, Tullio Scopigno |
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| Rok vydání: | 2017 |
| Předmět: |
Materials science
lcsh:Medicine 02 engineering and technology 01 natural sciences Article law.invention 010309 optics symbols.namesake Optics law 0103 physical sciences Microscopy Coherent Raman microscopy lcsh:Science balanced detection Birefringence Multidisciplinary business.industry Replica lcsh:R Nonlinear optics Stimulated Raman Scattering 021001 nanoscience & nanotechnology Laser stimulated Raman scattering symbols lcsh:Q 0210 nano-technology business Raman spectroscopy Sensitivity (electronics) Raman scattering |
| Zdroj: | Scientific Reports Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017) Scientific reports (Nature Publishing Group) 7 (2017). doi:10.1038/s41598-017-09839-1 info:cnr-pdr/source/autori:Crisafi, Francesco; Kumar, Vikas; Scopigno, Tullio; Marangoni, Marco; Cerullo, Giulio; Polli, Dario/titolo:In-line balanced detection stimulated Raman scattering microscopy/doi:10.1038%2Fs41598-017-09839-1/rivista:Scientific reports (Nature Publishing Group)/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume:7 |
| ISSN: | 2045-2322 |
| Popis: | We introduce a novel configuration for stimulated Raman scattering (SRS) microscopy, called In-line Balanced Detection (IBD), which employs a birefringent plate to generate a time-delayed polarization-multiplexed collinear replica of the probe, acting as a reference. Probe and reference cross the sample at the same position, thus maintaining their balance during image acquisition. IBD can be implemented in any conventional SRS setup, by adding a few simple elements, bringing its sensitivity close to the shot-noise limit even with a noisy laser. We tested IBD with a fiber-format laser system and observed signal-to-noise ratio improvement by up to 30 dB. |
| Databáze: | OpenAIRE |
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