Three-phase study of phlebitis in patients receiving peripheral intravenous hyperalimentation
| Autor: | I. James Sarfeh, Beverly H. Johnson, Eric B. Rypins, Sr. Barbara Reder, Kathi Shimoda |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Glycerol
medicine.medical_specialty Peripheral intravenous Random Allocation Catheters Indwelling Intravenous fluid Double-Blind Method Prevalence Humans Medicine In patient Prospective Studies Amino Acids Prospective cohort study Retrospective Studies Random allocation Bacteria business.industry Osmolar Concentration Retrospective cohort study General Medicine Peripheral Surgery Glucose Anesthesia Parenteral Nutrition Total Phlebitis business Filtration |
| Zdroj: | The American Journal of Surgery. 159:222-225 |
| ISSN: | 0002-9610 |
| Popis: | We found clinical phlebitis in 57 of 88 patients with peripheral hyperalimentation (65%). To determine if this was a problem common to all intravenous fluid therapy at our hospital, we performed a point-prevalence study. The prevalence of phlebitis in nonhyperalimentation intravenous patients was 18% (84 of 456 patients). We then performed a randomized, prospective, double-blind trial of sham versus standard in-line filters to determine if bacteria or filterable particulate matter was responsible for phlebitis in the peripheral hyperalimentation group. The standard-filter group had a phlebitis rate of 74% compared with 64% in the sham-filter group. We then eliminated in-line filters and replaced the standard glucose-based solution with a glycerol-based peripheral hyperalimentation solution. The phlebitis rate decreased from 68% to 27% (p less than 0.001). In conclusion, phlebitis in peripheral hyperalimentation patients was probably due to chemical properties of the peripheral hyperalimentation solution rather than bacteria or particulates. |
| Databáze: | OpenAIRE |
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