Epidemiology of methicillin-resistant Staphylococcus aureus lineages in five major African towns: emergence and spread of atypical clones
| Autor: | P. Boisier, Régis Pouillot, Benoit Garin, Jerome Etienne, Sylvain Brisse, S.B. Zriouil, Sébastien Breurec, S. Djibo, Frédérique Randrianirina, M.C. Fonkoua, Frédéric Laurent, C.E. Ramarokoto, Jean-David Perrier-Gros-Claude, Cheikh Fall, Jean-Michel Thiberge, Adama Tall |
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| Přispěvatelé: | Bactériologie médicale et Environnementale, Institut Pasteur de Dakar, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Faculté des Sciences et Techniques [Settat] (FSTS), Université Hassan 1er [Settat], Centre de Recherche Médicale et Sanitaire (Niamey, Niger) (CERMES), Réseau International des Instituts Pasteur (RIIP), Génotypage des Pathogènes et Santé Publique (Plate-forme) (PF8), Institut Pasteur [Paris], Centre National de Reference des Staphylocoques, Université de Lyon, Centre Pasteur du Cameroun, Institut Pasteur du Maroc, Institut Pasteur de Madagascar, Institut Pasteur [Paris] (IP) |
| Rok vydání: | 2011 |
| Předmět: |
Male
Leukocidin medicine.disease_cause 0302 clinical medicine Leukocidins Pandemic Epidemiology Cluster Analysis 030212 general & internal medicine Child Aged 80 and over Molecular Epidemiology 0303 health sciences General Medicine Middle Aged Staphylococcal Infections Bacterial Typing Techniques 3. Good health Community-Acquired Infections Infectious Diseases Staphylococcus aureus Child Preschool Female Adult Methicillin-Resistant Staphylococcus aureus clone (Java method) Microbiology (medical) hospital infections medicine.medical_specialty Adolescent Bacterial Toxins Exotoxins Biology Young Adult 03 medical and health sciences clones parasitic diseases medicine Humans Panton–Valentine leukocidin Aged Genetic diversity 030306 microbiology Genetic Variation Infant [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology Methicillin-resistant Staphylococcus aureus Virology Molecular Typing Africa |
| Zdroj: | Clinical Microbiology and Infection Clinical Microbiology and Infection, Elsevier for the European Society of Clinical Microbiology and Infectious Diseases, 2011, 17 (2), pp.160-5. ⟨10.1111/j.1469-0691.2010.03219.x⟩ Clinical Microbiology and Infection, 2011, 17 (2), pp.160-5. ⟨10.1111/j.1469-0691.2010.03219.x⟩ |
| ISSN: | 1198-743X 1469-0691 |
| DOI: | 10.1111/j.1469-0691.2010.03219.x |
| Popis: | International audience; The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) in Africa is poorly documented. From January 2007 to March 2008, we collected 86 MRSA isolates from five African towns, one each in Cameroon, Madagascar, Morocco, Niger and Senegal. Although one or two major clones, defined by the sequence type and staphylococcal cassette chromosome mec type, predominated at each site, genetic diversity (ten clones) was relatively limited in view of the large geographical area studied. Most of the isolates (n = 76, 88%) belonged to three major clones, namely ST239/241-III, a well-known pandemic clone (n = 34, 40%), ST88-IV (n = 24, 28%) and ST5-IV (n = 18, 21%). The latter two clones have only been sporadically described in other parts of the world. The spread of community-associated MRSA carrying the Panton-Valentine leukocidin genes is a cause for concern, especially in Dakar and possibly throughout Africa. |
| Databáze: | OpenAIRE |
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