Chikungunya fever outbreak identified in North Bali, Indonesia
| Autor: | Ni Putu Diah Witari, Ungke Anton Jaya, Putu Dwi Adi, Rama Dhenni, Chairin Nisa Ma'roef, Aditya Perkasa, Khin Saw Aye Myint, Ann M. Powers, Kartika Sari, Dewi Megawati, Ayu Rai Andayani |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Fever Genotype 030231 tropical medicine Enzyme-Linked Immunosorbent Assay Real-Time Polymerase Chain Reaction medicine.disease_cause Chikungunya fever Article Virus Disease Outbreaks Serology Young Adult 03 medical and health sciences 0302 clinical medicine medicine Humans 030212 general & internal medicine Chikungunya Aged Travel Public health Public Health Environmental and Occupational Health virus diseases Outbreak Febrile illness General Medicine Middle Aged Virology Infectious Diseases Geography Immunoglobulin M Indonesia Chikungunya Fever Female Parasitology Public Health Chikungunya virus |
| Zdroj: | Transactions of The Royal Society of Tropical Medicine and Hygiene. 111:325-327 |
| ISSN: | 1878-3503 0035-9203 |
| DOI: | 10.1093/trstmh/trx054 |
| Popis: | BACKGROUND: Chikungunya virus (CHIKV) infections have been reported sporadically within the last 5 years in several areas of Indonesia including Bali. Most of the reports, however, have lacked laboratory confirmation. METHOD: A recent fever outbreak in a village in the North Bali area was investigated using extensive viral diagnostic testing including both molecular and serological approaches. RESULTS AND CONCLUSIONS: Ten out of 15 acute febrile illness samples were confirmed to have CHIKV infection by real-time PCR or CHIKV-specific IgM enzyme-linked immunosorbent assay (ELISA). The outbreak strain belonged to the Asian genotype with highest homology to other CHIKV strains currently circulating in Indonesia. The results are of public health concern particularly because Bali is a popular tourist destination in Indonesia and thereby the potential to spread the virus to non-endemic areas is high. GENBANK ACCESSION NUMBERS: KY885022, KY885023, KY885024, KY885025, KY885026, KY885027. |
| Databáze: | OpenAIRE |
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