Occurrence of Leishmania sp. in cutaneous lesions of horses in Central Europe
| Autor: | Wolf von Bomhard, Monika Hilbe, Caroline F. Frey, Monika Maria Welle, Lisbeth Lobsiger, Norbert Müller, Michael Hubert Stoffel, Kathrin Kühni Boghenbor, Claudia Geyer, Bruno Gottstein |
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| Přispěvatelé: | University of Zurich, Müller, N |
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Male
Pathology medicine.medical_specialty Old World 3400 General Veterinary Molecular Sequence Data 2405 Parasitology 10184 Institute of Veterinary Pathology Biology Cutaneous leishmaniasis Genotype medicine Animals Horses Skin Diseases Parasitic Internal transcribed spacer 610 Medicine & health Genotyping Leishmaniasis Phylogeny Leishmania General Veterinary Base Sequence 630 Agriculture General Medicine medicine.disease Virology Europe Visceral leishmaniasis Parasitology 570 Life sciences biology Female Horse Diseases Sequence Alignment |
| DOI: | 10.7892/boris.37775 |
| Popis: | The present report describes a novel etiological agent of cutaneous leishmaniasis in horses that, at least for some cases, sporadically appeared as autochthonous infections in geographically distant regions of Germany and Switzerland. The infection was initially diagnosed upon clinical and immunohistological findings. Subsequent comparative sequence analysis of diagnostic PCR products from the internal transcribed spacer 1 (ITS1) of ssrRNA classified the respective isolates as neither Old World nor New World Leishmania species. However, four isolates subjected to molecular analyses all exhibited a close phylogenetic relationship to Leishmania sp. siamensis, an organism recently identified in a visceral leishmaniasis patient from Thailand. Future investigations will demonstrate if this form of leishmaniasis represents an emerging, and perhaps zoonotic, disease of European, or even global, importance. |
| Databáze: | OpenAIRE |
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