Occult left ventricular dysfunction diagnosed by myocardial performance index in patients with limb girdle muscle dystrophy: A case control study
| Autor: | Meena K. Angamutta, Venkata M. Alla, Sundaram Challa, Wilbert S. Aronow, Chandra K. Nair, Jai S. Shankar, Rajashekar R. Gurrala, Krishna S.R. Lanka |
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| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Pathology Ejection fraction business.industry Case-control study Limb girdle Muscle dystrophy Occult Cardiac dysfunction Internal medicine medicine Cardiology cardiovascular system In patient Original Article Myocardial Performance Index Cardiology and Cardiovascular Medicine business |
| Popis: | The myocardial performance index (MPI) was assessed in 30 patients with limb girdle muscle dystrophy (LGMD) with a normal left ventricular ejection fraction (greater than 50%), as well as in 30 age- and sex-matched healthy adults with a left ventricular ejection fraction greater than 50%. MPIs derived by pulsed-wave Doppler and tissue Doppler were also compared. The MPI was 0.37±0.09 in the LGMD patients and 0.29±0.09 in the control group (P=0.003). These data show that patients with LGMD have occult cardiac dysfunction as evidenced by a higher MPI than the controls. There was good agreement between the MPIs measured by pulsed-wave Doppler and tissue Doppler methods in these patients. |
| Databáze: | OpenAIRE |
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