High prevalence of TB disease in contacts of adults with extrapulmonary TB
| Autor: | Tom Wingfield, L Peter Ormerod, Peter MacPherson, Paul Cleary |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine wc_20 Pediatrics medicine.medical_specialty Tuberculosis Prevalence Nice Disease wc_200 03 medical and health sciences 0302 clinical medicine London Research Letter Humans Medicine 030212 general & internal medicine Tuberculosis Pulmonary Retrospective Studies computer.programming_language Transients and Migrants High prevalence business.industry Extrapulmonary tuberculosis Retrospective cohort study clinical epidemiology medicine.disease wa_300 3. Good health tuberculosis 030228 respiratory system Population Surveillance wf_220 Female wf_200 Contact Tracing business computer Contact tracing |
| Zdroj: | Thorax |
| ISSN: | 1468-3296 0040-6376 |
| DOI: | 10.1136/thoraxjnl-2017-210202 |
| Popis: | UK guidelines no longer recommend routine screening of household contacts of adult patients with extrapulmonary TB (EPTB). From 27 March 2012 to 28 June 2016, we investigated the prevalence of active TB disease in household contacts of 1023 EPTB index cases in North West England, and compared estimates with: published new entrant migrant screening programme prevalence (~147/100 000 person-years); London-based contact screening data (700/100 000 contacts screened); and National Institute for Health and Care Excellence (NICE) new entrant TB screening thresholds (TB prevalence >40/100 000 people). Active TB disease prevalence in EPTB contacts was 440/100 000 contacts screened, similar to UK new entrant screening programmes, London EPTB contact prevalence and >10 times NICE’s threshold for new entrant screening. The decision to no longer recommend routine screening of EPTB contacts should be re-evaluated and cost-effectiveness analyses of screening strategies for EPTB contacts should be performed. |
| Databáze: | OpenAIRE |
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