A51chromium isotope release assay for detecting cytotoxicity to human bladder carcinoma
| Autor: | Carol O'Toole |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Cancer Research
Time Factors Lysis Urinary Bladder Cell Count Cell Separation Biology urologic and male genital diseases Cryopreservation Cell Line Freezing Carcinoma medicine Humans Lymphocytes Cytotoxicity Cells Cultured Carcinoma Transitional Cell Immunity Cellular Isotope Effector Cytotoxicity Tests Immunologic medicine.disease Molecular biology Chromium Radioisotopes Immune Adherence Reaction Transitional cell carcinoma Urinary Bladder Neoplasms Oncology Cell culture Tissue Preservation |
| Zdroj: | International Journal of Cancer. 19:324-331 |
| ISSN: | 1097-0215 0020-7136 |
| DOI: | 10.1002/ijc.2910190307 |
| Popis: | A 51chromium isotope release assay is described for measuring in vitro cytotoxicity reactions against allogenetic target cells. Lymphoid cells from some patients with localized transitional cell carcinoma (TCC) were shown to selectively lyse targets derived from two long-term cell lines of TCC. The effector cells in this reaction did not form E rosettes. Cytotoxicity was successfully recovered after cryopreservation. |
| Databáze: | OpenAIRE |
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