Plasma cholesterol and triglyceride levels in 6,775 school children, ages 6--17
| Autor: | Jerry L. Rauh, John A. Morrison, Ido deGroot, Brenda K. Edwards, Charles J. Glueck, Margot J. Mellies, Kathe A. Kelly |
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| Rok vydání: | 1977 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Endocrinology Diabetes and Metabolism Black People Hyperlipidemias Target population School district White People chemistry.chemical_compound Endocrinology Sex Factors Plasma cholesterol Internal medicine Plasma lipids Medicine Humans Child Triglycerides Ohio Triglyceride business.industry Cholesterol Age Factors chemistry Female business Hormone |
| Zdroj: | Metabolism: clinical and experimental. 26(11) |
| ISSN: | 0026-0495 |
| Popis: | Associations of age, sex, and race with the distribution of fasting plasma cholesterol and triglyceride were studied in 6775 school children (4946 white and 1829 black students, ages 6–17 yr) in a biethnic school district. The target population included 8906 students with 84% of eligible white and 78% of eligible black children participating. In children ages 6–10, mean cholesterol and triglyceride levels varied only minimally. Females 6–10 yr old generally had higher mean plasma cholesterol and triglyceride than males, and blacks had higher mean cholesterol and lower mean triglyceride than whites, p < 0.001. In comparison to the cross-sectional stability of cholesterol and triglyceride over ages 6–10, plasma cholesterol began to fall at ages 11 and 12, continued to fall through ages 15–16, and rose at age 17. An inverse pattern was observed for mean triglycerides. The major increment in triglyceride levels occurred between the ages of 11 and 12, temporally concordant with decrements in cholesterol. Subsequently, in males mean triglycerides continued to rise through age 17, while in females mean triglycerides dipped sharply at ages 16 and 17. Withinrace comparisons of changes in triglyceride over age show the males first having lower triglyceride than females at ages 11–13, and the female levels falling below the male levels at ages 15–17. The decrements of cholesterol and increments in triglyceride during adolescence were also generally observed for the extremes of the distribution, the 5th and 95th percentiles. As was the case for 6–11-yr olds, in the 12–17-yr-old children, blacks had higher mean cholesterols and lower mean triglycerides than whites. Within the limitations of the cross-sectional nature of this study, the inverse changes of cholesterol and triglyceride suggest that hormonal and growth changes during adolescence may have a notable effect on plasma lipids. The availability of age-, sex-, and race-specific cholesterol and triglyceride distributions may allow more meaningful assessment of plasma cholesterol and triglyceride levels of any individual child. |
| Databáze: | OpenAIRE |
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