Design of enzyme inhibitors using iterative protein crystallographic analysis
| Autor: | K, Appelt, R J, Bacquet, C A, Bartlett, C L, Booth, S T, Freer, M A, Fuhry, M R, Gehring, S M, Herrmann, E F, Howland, C A, Janson |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
chemistry.chemical_classification
Crystallography biology Stereochemistry Stereoisomerism Microbial Sensitivity Tests Thymidylate Synthase Crystal structure Thymidylate synthase Structure-Activity Relationship Enzyme Investigation methods chemistry Enzyme inhibitor Drug Design Drug Discovery Escherichia coli biology.protein Humans Molecular Medicine Molecule Enzyme Inhibitors |
| Zdroj: | Journal of Medicinal Chemistry. 34:1925-1934 |
| ISSN: | 1520-4804 0022-2623 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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