| Autor: |
Michael J. Littau, Corinne Bunn, Preston Kim, Sujay Kulshrestha, Celsa Tonelli, Zaid M. Abdelsattar, Fred A. Luchette, Marshall S. Baker |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
The American Journal of Surgery. 223:527-530 |
| ISSN: |
0002-9610 |
| DOI: |
10.1016/j.amjsurg.2021.12.026 |
| Popis: |
Few studies evaluate the efficacy of adjuvant radiotherapy (aXRT) in patients with retroperitoneal liposarcoma undergoing resection to histologically positive (R1) margins.We queried the National Cancer Database to identify patients undergoing R1 resection for localized, large (5 cm) low and moderate grade retroperitoneal liposarcoma between 2004 and 2016. Kaplan Meier method was used to compare overall survival (OS) for patients receiving aXRT to a 1:2 propensity-matched cohort of patients undergoing resection alone.A total of 322 (76.5%) patients underwent R1 resection alone, while 99 (23.5%) underwent resection followed by aXRT. The 99 receiving aXRT were successfully 1:2 propensity-score matched to 198 undergoing resection alone. There was no difference in 5-year OS between matched cohorts (69.7% vs 76.2%, p = 0.40).In patients undergoing R1 resection of moderate- and well-differentiated retroperitoneal liposarcoma, use of aXRT is not associated with an improvement in OS. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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