Studies on the prevalence of Hepatitis C virus infection in diabetic patients attending a tertiary health-care facility South-west Nigeria

Autor: Akinyomade Owolabi, Jeremiah A. Akinwumi, James A. Ndako, Victor T. Dojumo, Joseph A. Olisa, Blessing A. Adebayo, Oludolapo Olatinsu
Rok vydání: 2019
Předmět:
Male
Comorbidity
Hepacivirus
medicine.disease_cause
Tertiary Care Centers
0302 clinical medicine
Medical microbiology
Risk Factors
Surveys and Questionnaires
Epidemiology
Prevalence
030212 general & internal medicine
Child
Aged
80 and over
Mortality rate
Hepatitis C
Middle Aged
Type 2 diabetes mellitus (T2DM)
Infectious Diseases
Child
Preschool
HCV
030211 gastroenterology & hepatology
Female
Research Article
Adult
medicine.medical_specialty
Adolescent
Patients
Hepatitis C virus
Nigeria
Enzyme-Linked Immunosorbent Assay
lcsh:Infectious and parasitic diseases
03 medical and health sciences
Young Adult
Internal medicine
Diabetes mellitus
medicine
Humans
lcsh:RC109-216
Aged
business.industry
Public health
Infant
Newborn
Type 2 Diabetes Mellitus
Infant
Hepatitis C Antibodies
medicine.disease
Diabetes Mellitus
Type 2
business
Zdroj: BMC Infectious Diseases
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-10 (2020)
ISSN: 1471-2334
Popis: Background Hepatitis C virus (HCV) infection and type 2 diabetes mellitus (T2DM) are two major public health problems associated with increasing complications and mortality rates worldwide. The objective of this study is to evaluate the prevalence of hepatitis C virus (HCV) infection in diabetic patients and to investigate the influence of several epidemiological and clinical factors on HCV infection. Method A total number of one hundred and eighty diabetic patients were recruited for this study. Consented subjects made up of 71(39.4%) males and 109(60.56%) females were recruited for the study. While one-Hundred (100) Non-Diabetics (Controls) were also recruited for the study. Structured questionnaires were administered to the consented participants to obtain relevant data. Sera samples were assayed for antibodies to HCV using an enzyme linked immunosorbent assay [Inteco Diagnostic Limited]. ELISA technique. Result Overall prevalence of HCV infection among diabetes patients assayed was 13.3% out of which 8(11.3%) was obtained from the male subjects compared to 16 (14.7%) seropositivity recorded among the females (P = 0.511; P > 0.05). Considering age distribution, Subjects aged 41–50 years recorded, 9 (22.5%) positivity (P = 0.238; P > 0.05).Considering educational status of subjects screened, 22 (14.9%) positivity was rescored among subjects who have attained tertiary status of education.(P = 0.574;P > 0.05).Risk factors considered showed that, 7 (18.9%) seropositive subject were alcoholic consumers(P value = 0.2621;P > 0.05) while 5 (8.9%) recorded history of sharing sharp objects P = 0.2427;P > 0.05). Conclusion Our study shows a slightly higher prevalence of hepatitis C infection in type 2 diabetics. This call for urgent routine screening exercise among diabetic patients for HCV infection. This study also emphasizes the need for public enlightenment on the association between HCV infection and T2DM, to avert possible complications among diabetic patients.
Databáze: OpenAIRE
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