Studies on the prevalence of Hepatitis C virus infection in diabetic patients attending a tertiary health-care facility South-west Nigeria
Autor: | Akinyomade Owolabi, Jeremiah A. Akinwumi, James A. Ndako, Victor T. Dojumo, Joseph A. Olisa, Blessing A. Adebayo, Oludolapo Olatinsu |
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Rok vydání: | 2019 |
Předmět: |
Male
Comorbidity Hepacivirus medicine.disease_cause Tertiary Care Centers 0302 clinical medicine Medical microbiology Risk Factors Surveys and Questionnaires Epidemiology Prevalence 030212 general & internal medicine Child Aged 80 and over Mortality rate Hepatitis C Middle Aged Type 2 diabetes mellitus (T2DM) Infectious Diseases Child Preschool HCV 030211 gastroenterology & hepatology Female Research Article Adult medicine.medical_specialty Adolescent Patients Hepatitis C virus Nigeria Enzyme-Linked Immunosorbent Assay lcsh:Infectious and parasitic diseases 03 medical and health sciences Young Adult Internal medicine Diabetes mellitus medicine Humans lcsh:RC109-216 Aged business.industry Public health Infant Newborn Type 2 Diabetes Mellitus Infant Hepatitis C Antibodies medicine.disease Diabetes Mellitus Type 2 business |
Zdroj: | BMC Infectious Diseases BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-10 (2020) |
ISSN: | 1471-2334 |
Popis: | Background Hepatitis C virus (HCV) infection and type 2 diabetes mellitus (T2DM) are two major public health problems associated with increasing complications and mortality rates worldwide. The objective of this study is to evaluate the prevalence of hepatitis C virus (HCV) infection in diabetic patients and to investigate the influence of several epidemiological and clinical factors on HCV infection. Method A total number of one hundred and eighty diabetic patients were recruited for this study. Consented subjects made up of 71(39.4%) males and 109(60.56%) females were recruited for the study. While one-Hundred (100) Non-Diabetics (Controls) were also recruited for the study. Structured questionnaires were administered to the consented participants to obtain relevant data. Sera samples were assayed for antibodies to HCV using an enzyme linked immunosorbent assay [Inteco Diagnostic Limited]. ELISA technique. Result Overall prevalence of HCV infection among diabetes patients assayed was 13.3% out of which 8(11.3%) was obtained from the male subjects compared to 16 (14.7%) seropositivity recorded among the females (P = 0.511; P > 0.05). Considering age distribution, Subjects aged 41–50 years recorded, 9 (22.5%) positivity (P = 0.238; P > 0.05).Considering educational status of subjects screened, 22 (14.9%) positivity was rescored among subjects who have attained tertiary status of education.(P = 0.574;P > 0.05).Risk factors considered showed that, 7 (18.9%) seropositive subject were alcoholic consumers(P value = 0.2621;P > 0.05) while 5 (8.9%) recorded history of sharing sharp objects P = 0.2427;P > 0.05). Conclusion Our study shows a slightly higher prevalence of hepatitis C infection in type 2 diabetics. This call for urgent routine screening exercise among diabetic patients for HCV infection. This study also emphasizes the need for public enlightenment on the association between HCV infection and T2DM, to avert possible complications among diabetic patients. |
Databáze: | OpenAIRE |
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