Sequencing and de novo assembly reveals genomic variations associated with differential responses of Candida albicans ATCC 10231 towards fluconazole, pH and non-invasive growth

Autor:	Gajanan B. Zore, Rajendra Patil, Bipin Balan, Chaithra Pradip, Archana D. Thakre
Rok vydání:	2018
Předmět:	Whole genome sequencing Genetics Sequence assembly Coding region Genomics Biology Candida albicans biology.organism_classification Gene Genome Corpus albicans
DOI:	10.1101/302943
Popis:	The whole genome sequencing generated 8.09 million paired-end reads, which were assembled into 2,262 scaffolds totaling 17,113,050 bp in length. We predict 7,654 coding regions and 7,647 genes, and annotated the coding regions with gene ontology terms based on similarity to other annotated genomes. Genome comparisons revealed variations (including SNP and indels in genes involved in pH response, fluconazole resistance and invasive growth) compared to C. albicans SC5314 and WO1.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122fdbdc31f3eec2a9f9d5d068d62f6a https://doi.org/10.1101/302943 Zobrazit plný text záznamu