Three-factor model of premorbid adjustment in a sample with chronic schizophrenia and first-episode psychosis

Autor: Susana Ochoa, Judith Usall, Alexandrina Foix, Ana Barajas, Bernardo Sánchez, Jaume Autonell, Miriam Vilaplana, Iris Baños, Jorge A. Cervilla, Jordi E. Obiols, Victoria Villalta-Gil, Montserrat Dolz, Josep Maria Haro
Rok vydání: 2013
Předmět:
Zdroj: Schizophrenia Research. 151:252-258
ISSN: 0920-9964
Popis: article i nfo Background: The dimensionality of premorbid adjustment (PA) has been a debated issue, with attempts to determine whether PA is a unitary construct or composed of several independent domains characterized by a differential deterioration pattern and specific outcome correlates. Aims: This study examines the factorial structure of PA, as well as, the course and correlates of its domains. Method: Retrospective study of 84 adult patients experiencing first-episode psychosis (FEP) (n = 33) and individuals with schizophrenia (SCH) (n = 51). All patients were evaluated with a comprehensive battery of instruments including clinical, functioning and neuropsychological variables. A principal component analysis accompanied by a varimax rotation method was used to examine the factor structure of the PAS-S scale. Paired t tests and Wilcoxon rank tests were used toassess the changes in PAS domains over time. Bivariate correlation anal- yses were performed to analyse the relationship between PAS factors and clinical, social and cognitive variables. Results: PA was better explained by three factors (71.65% of the variance): Academic PA, Social PA and Socio-sexual PA. The academic domain showed higher scores of PA from childhood. Social and clinical variables were more strongly related to Social PA and Socio-sexual PA domains, and the Academic PA domain was exclusively associated with cognitive variables. Conclusion: This study supports previous evidence, emphasizing the validity of dividing PA into its sub-components. A differential deterioration pattern and specific correlates were observed in each PA domains, suggesting that impairments in each PA domain might predispose individuals to develop different expressions of psychotic dimensions.
Databáze: OpenAIRE