Risk Factors Associated with Ascending Aortic Aneurysms and Aortic Elasticity Parameters in Children with a Bicuspid Aortic Valve
| Autor: | Ahmet Çelebi, İlker Kemal Yücel, Taliha Öner, Gökmen Akgün, Selma Oktay Ergin, Huseyin Karadag |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Aortic Valve Insufficiency Heart Valve Diseases 030204 cardiovascular system & hematology Lesion 03 medical and health sciences 0302 clinical medicine Bicuspid aortic valve Vascular Stiffness Bicuspid Aortic Valve Disease Risk Factors medicine.artery Internal medicine Ascending aorta Medicine Humans Child Aorta business.industry Aortic Valve Stenosis Vascular surgery medicine.disease Cardiac surgery Aortic Aneurysm Stenosis Blood pressure 030228 respiratory system Echocardiography Aortic Valve Case-Control Studies Pediatrics Perinatology and Child Health cardiovascular system Cardiology Aortic stiffness Female medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | Pediatric cardiology. 40(5) |
| ISSN: | 1432-1971 |
| Popis: | Aneurysms of the ascending aorta are frequently found in patients with a bicuspid aortic valve (BAV). This study assessed the risk factors of ascending aortic aneurysms and aortic elasticity in children with BAV. The study included 66 patients with no history of transcatheter intervention or surgical procedure who had been diagnosed with isolated BAV. Echocardiographic, blood pressure, and pulse measurements were obtained for all patients. The BAVs were classified as described by Sievers et al. (J Thorac Cardiovasc Surg 133:1226–1233, 2007), and aortic elasticity parameters were calculated using various formulas. The patients were divided into groups with and without cusp fusion, aortic stenosis (AS), aortic regurgitation (AR), or mixed lesions; the groups were then compared. The mean patient age was 10.43 ± 3.91 years; 15%he patients had no AS or AR, 33% had both AS and AR, 17% had AS alone, and 35% had AR alone. The most common type of BAV was type 5, and the ascending aorta z-scores were higher in children with mixed lesions and without a cusp fusion. Aortic distensibility (AD) was significantly higher, and the stiffness index was significantly lower, in patients with an ascending aorta z-score > 4. The ascending aortic z-scores were higher in the no-fusion and mixed lesion (AS + AR) groups, especially those originating from post-stenotic dilation due to AS. The AD was increased in patients with an ascending aorta z-score > 4. Patients should thus be monitored closely for dissection risk, and preventive medical treatment should be started early in those with AS without cusp fusion. |
| Databáze: | OpenAIRE |
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