Acute muscular paralysis in an adult with subclinical Bartter's syndrome associated with gentamicin administration
| Autor: | Ching-Jyh Shiah, Siauw Cp, Shue-Tsong Liao, Long-Shyong Lee, Dong-Ming Tsai |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Adult
medicine.medical_specialty endocrine system diseases urologic and male genital diseases Bartter syndrome Plasma renin activity Asymptomatic Hypomagnesemia Muscular Diseases Internal medicine medicine Humans Paralysis business.industry Bartter Syndrome medicine.disease Hyperaldosteronism Hypokalemia Bartter's syndrome Endocrinology Nephrology Kaliuresis Acute Disease Female medicine.symptom Gentamicins business |
| Zdroj: | American journal of kidney diseases : the official journal of the National Kidney Foundation. 24(6) |
| ISSN: | 0272-6386 |
| Popis: | We report an adult case of asymptomatic Bartter's syndrome with the first presentation of hypokalemic paralysis triggered by gentamicin injection. Marked hypokalemia and hypomagnesemia associated with excessive kaliuresis and magnesiuria were found. Plasma renin activity and aldosterone concentration were high, but blood pressure was normal. Renal biopsy revealed hypercellularity of the renin-producing cell of the juxtaglomerular apparatus. Muscular paralysis subsided after potassium chloride supplementation. Hypokalemia was corrected with potassium and magnesium supplements and the use of diclofenac. To the best of our knowledge, there have been no reports of muscular paralysis associated with gentamicin in Bartter's syndrome. |
| Databáze: | OpenAIRE |
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