Exercise plus presleep protein ingestion increases overnight muscle connective tissue protein synthesis rates in healthy older men
| Autor: | Imre W. K. Kouw, Joy P B Goessens, Janneau van Kranenburg, Andrew M. Holwerda, Lex B. Verdijk, Joan M. G. Senden, Jorn Trommelen, Luc J. C. van Loon, Annemie P. Gijsen |
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| Přispěvatelé: | Physiotherapy, Human Physiology and Anatomy, Human Physiology and Sports Physiotherapy Research Group, Humane Biologie, RS: NUTRIM - R3 - Respiratory & Age-related Health, RS: NUTRIM - R1 - Obesity, diabetes and cardiovascular health |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Blood Glucose
Male STIMULATION collagen Muscle Proteins Medicine (miscellaneous) Stimulation Connective Tissue/metabolism Sleep/physiology 0302 clinical medicine Myofibrils Casein Protein biosynthesis Insulin Orthopedics and Sports Medicine LATERAL TRANSMISSION Muscle Proteins/biosynthesis RESISTANCE EXERCISE Nutrition and Dietetics Caseins Postprandial Period/physiology Blood Proteins General Medicine Postprandial Period medicine.anatomical_structure Postprandial Caseins/administration & dosage Connective Tissue WHEY Elder Nutritional Physiological Phenomena Dietary Proteins Muscle tissue medicine.medical_specialty injury Phenylalanine Connective tissue 030209 endocrinology & metabolism Blood Proteins/analysis Myofibrils/metabolism FORCE Dietary Proteins/administration & dosage 03 medical and health sciences Double-Blind Method Leucine Internal medicine medicine EXTRACELLULAR-MATRIX Humans Muscle Skeletal SKELETAL-MUSCLES Aged Muscle Skeletal/metabolism business.industry aging 030229 sport sciences Blood Glucose/analysis Resistance training Endocrinology Leucine/administration & dosage Connective tissue metabolism Phenylalanine/administration & dosage Sleep Myofibril business Insulin/blood |
| Zdroj: | International Journal of Sport Nutrition and Exercise Metabolism, 31(3), 217-226. Human Kinetics Publishers |
| ISSN: | 1526-484X |
| Popis: | Protein ingestion and exercise stimulate myofibrillar protein synthesis rates. When combined, exercise further increases the postprandial rise in myofibrillar protein synthesis rates. It remains unclear whether protein ingestion with or without exercise also stimulates muscle connective tissue protein synthesis rates. The authors assessed the impact of presleep protein ingestion on overnight muscle connective tissue protein synthesis rates at rest and during recovery from resistance-type exercise in older men. Thirty-six healthy, older men were randomly assigned to ingest 40 g intrinsically L-[1-13C]-phenylalanine and L-[1-13C]-leucine-labeled casein protein (PRO, n = 12) or a nonprotein placebo (PLA, n = 12) before going to sleep. A third group performed a single bout of resistance-type exercise in the evening before ingesting 40 g intrinsically-labeled casein protein prior to sleep (EX+PRO, n = 12). Continuous intravenous infusions of L-[ring-2H5]-phenylalanine and L-[1-13C]-leucine were applied with blood and muscle tissue samples collected throughout overnight sleep. Presleep protein ingestion did not increase muscle connective tissue protein synthesis rates (0.049 ± 0.013 vs. 0.060 ± 0.024%/hr in PLA and PRO, respectively; p = .73). Exercise plus protein ingestion resulted in greater overnight muscle connective tissue protein synthesis rates (0.095 ± 0.022%/hr) when compared with PLA and PRO (p p de novo muscle connective tissue protein synthesis during overnight sleep. |
| Databáze: | OpenAIRE |
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