Comparison of Muscle Functional Electrical Stimulation to Conventional Bicycle Exercise on Endothelium and Functional Status Indices in Patients With Heart Failure
| Autor: | Olga Ntzouvara, Vasiliki Panagopoulou, Vlasios Pyrgakis, Christodoulos Stefanadis, Apostolos Karavidas, Georgios Giannopoulos, Andreas Kaoukis, Charalampos Kossyvakis, Metaxia Driva, Konstantinos Raisakis, Loukas K. Pappas, Ilias Rentoukas, Constadina Aggeli, Spyridon Deftereos |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Adult
Male medicine.medical_specialty Brachial Artery Heart disease Electric Stimulation Therapy Physical exercise Internal medicine medicine.artery medicine Humans Functional electrical stimulation Prospective Studies Exercise physiology Brachial artery Muscle Skeletal Prospective cohort study Exercise Aged Heart Failure Leg Cross-Over Studies Ejection fraction business.industry Middle Aged medicine.disease Exercise Therapy Vasodilation Treatment Outcome Heart failure Exercise Test Cardiology Female Endothelium Vascular Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | The American Journal of Cardiology. 106:1621-1625 |
| ISSN: | 0002-9149 |
| Popis: | The aim of this prospective, open-label, cohort study was to compare the effect of muscle functional electrical stimulation (FES) on endothelial function to that of conventional bicycle training. Eligible patients were those with New York Heart Association class II or III heart failure symptoms and ejection fractions ≤ 0.35. Two physical conditioning programs were delivered: FES of the muscles of the lower limbs and bicycle training, each lasting for 6 weeks, with a 6-week washout period between them. Brachial artery flow-mediated dilation (FMD) and other parameters were assessed before and after FES and the bicycle training program. FES resulted in a significant improvement in FMD, which increased from 5.9 ± 0.5% to 7.7 ± 0.5% (95% confidence interval for the difference 1.5% to 2.3%, p0.001). Bicycle training also resulted in a substantial improvement of endothelial function. FMD increased from 6.2 ± 0.4% to 9.2 ± 0.4% (95% confidence interval for the difference 2.5% to 3.5%, p0.001). FES was associated with a 41% relative increase in FMD, compared to 57% with bicycle exercise (95% confidence interval for the difference between the relative changes 1.2% to 30.5%, p = 0.034). This resulted in attaining a significantly higher FMD value after bicycle training compared to FES (9.2 ± 0.4% vs 7.7 ± 0.5%, p0.001). In conclusion, the effect of muscle FES in patients with heart failure on endothelial function, although not equivalent to that of conventional exercise, is substantial. Muscle FES protocols may prove very useful in the treatment of patients with heart failure who cannot or will not adhere to conventional exercise programs. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect