Occurrence of ceramides and neutral glycolipids with unusual long-chain base composition in purified rat liver mitochondria
| Autor: | Luc Thomas, Alexandre Pons, Iuliana Popa, J.P. Zanetta, Dominique Ardail, K Alcantara, Pierre Louisot, Jacques Portoukalian |
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| Rok vydání: | 2001 |
| Předmět: |
Ketosphinganine
Ceramide Neutral Glycosphingolipids Biophysics Lactosylceramides Mitochondria Liver Biology Mitochondrion Ceramides Glucosylceramides Biochemistry Gas Chromatography-Mass Spectrometry chemistry.chemical_compound Lactosylceramide Glycolipid Structural Biology Antigens CD Sphingosine Genetics Animals music Molecular Biology Glycosphingolipid music.instrument Fatty Acids Cell Biology Intracellular Membranes Rats Membrane chemistry Composition (visual arts) |
| Zdroj: | FEBS letters. 488(3) |
| ISSN: | 0014-5793 |
| Popis: | The free ceramide content of rat liver mitochondria was found to be 1.7 nmol/mg protein and outer membranes contained a three-fold higher concentration than inner membranes. The mitochondrial content in neutral glycolipids was 0.6 nmol/mg protein. The long-chain bases found in free ceramides were d18:1 sphingosine, d18:0 3-ketosphinganine and t21:1 phytosphingosine in increasing order. In contrast, 3-ketosphinganine was the only base of glucosylceramide and lactosylceramide of inner membranes, whereas d18:1 sphingosine was the major long-chain base of glucosylceramide of outer membranes. |
| Databáze: | OpenAIRE |
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