Clinical factors associated with successful embolization of lower gastrointestinal bleeding
| Autor: | Benjamin Loveday, Greg O'Grady, Bert van der Werf, Sanjay Pandanaboyana, Navamayooran Thavanesan, Adil Shafi, Colette Kennedy |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Lower gastrointestinal bleeding Multivariate analysis medicine.medical_treatment 03 medical and health sciences 0302 clinical medicine medicine Humans Embolization Retrospective Studies Univariate analysis medicine.diagnostic_test business.industry Angiography Digital Subtraction Retrospective cohort study General Medicine Digital subtraction angiography medicine.disease Embolization Therapeutic body regions Treatment Outcome 030220 oncology & carcinogenesis Angiography 030211 gastroenterology & hepatology Surgery Radiology Gastrointestinal Hemorrhage business Partial thromboplastin time |
| Zdroj: | ANZ Journal of Surgery. 91:2097-2105 |
| ISSN: | 1445-2197 1445-1433 |
| Popis: | AIM To develop a model of clinical factors that may predict: (1) technically and clinically successful embolization of a bleeding vessel at digital subtraction angiography (DSA) for lower gastrointestinal bleed (LGIB); (2) a negative DSA in the presence of positive CT-mesenteric angiography (CTMA) for LGIB. METHODS A retrospective cohort study of all DSAs conducted with intent for embolization for acute LGIB over a 10-year period was undertaken. Pre-procedural and intra-procedural clinical variables were evaluated using uni- and multi-variate analysis. RESULTS One hundred and twenty-three DSAs were evaluated. Technical success was 81% and clinical success 78% where DSA was positive. Technical success was associated with super-selective approach, contrast extravasation on CT, haemoglobin drop, anatomical source and time from CT to DSA on univariate analysis. On multivariate analysis, time from CT to DSA was significant with a higher success probability within 120 min with different factors being salient depending on degree of delay. Clinical success was only associated with activated partial thromboplastin time ( |
| Databáze: | OpenAIRE |
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