Optimizing ADAS-Cog Worksheets: A Survey of Clinical Trial Rater s’ Perceptions
| Autor: | Magdalena Perez, Kimberly Schafer, Sarah Walter, Kristina Bertzos, Donald J. Connor, Stephen M. Meyer |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Standardization Neuropsychological Tests behavioral disciplines and activities 03 medical and health sciences Cognition 0302 clinical medicine Documentation Alzheimer Disease Surveys and Questionnaires mental disorders Humans Medicine Cognitive skill Reliability (statistics) Clinical Trials as Topic business.industry fungi Neuropsychology Reproducibility of Results Research Personnel Test (assessment) Clinical trial 030104 developmental biology Neurology Educational Status Neurology (clinical) business human activities 030217 neurology & neurosurgery Specialization Clinical psychology |
| Zdroj: | Current Alzheimer Research. 14 |
| ISSN: | 1567-2050 |
| DOI: | 10.2174/1567205014666170417122744 |
| Popis: | The Alzheimer’s Disease Assessment Scale-Cognitive subscale (ADAS-Cog) remains the most widely used test of longitudinal cognitive functioning in Alzheimer’s disease (AD) clinical trials. Unlike most neuropsychological tests, the ADAS-Cog source documentation worksheets are not uniform across clinical trials, and vary by document layout, inclusion of administration and/or scoring instructions, and documentation of subtest scoring (e.g., recording correct versus incorrect scores), among other differences. Many ADAS-Cog test administrators (raters) participate in multiple AD trials and switching between different ADAS-Cog worksheets may increase the likelihood of administration and/or scoring mistakes that lessen the reliability of the instrument. An anonymous online survey sought raters’ experiences with ADAS-Cog worksheets and their opinions on the design and content of the worksheets. Results of the survey indicated preference for structure and standardization of the ADAS-Cog worksheets, which has been considered in the development of a standard ADAS-Cog source document by the Alzheimer’s Disease Cooperative Study (ADCS) Working Group |
| Databáze: | OpenAIRE |
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