Molecular epidemiology of vancomycin-resistant Enterococcus faecium infecting recipients of solid organs in the transplant surgery ward in 2005 and 2006
| Autor: | T. Buczkowska, A. Kwiatkowski, L. Adadynski, Grażyna Młynarczyk, Leszek Paczek, A. Mrowka, Magdalena Durlik, Andrzej Młynarczyk, W. Grzybowska, Joanna Pazik, Stefan Tyski, Andrzej Chmura |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
DNA
Bacterial medicine.drug_class Antibiotics Enterococcus faecium Drug resistance Urine Restriction fragment Microbiology Medicine Bile Humans Gram-Positive Bacterial Infections Molecular Epidemiology Transplantation biology Molecular epidemiology business.industry Outbreak Vancomycin Resistance biochemical phenomena metabolism and nutrition bacterial infections and mycoses biology.organism_classification Kidney Transplantation Electrophoresis Gel Pulsed-Field Liver Transplantation Immunology biology.protein Vancomycin Surgery business Polymorphism Restriction Fragment Length medicine.drug |
| Zdroj: | Transplantation proceedings. 41(8) |
| ISSN: | 1873-2623 |
| Popis: | Background The aim of the investigations was to compare the vancomycin-resistant Enterococcus faecium (VREfm) strains obtained from our patients. Materials and Methods Strains were compared using restriction fragment length polymorphism–pulsed field gel electrophoresis (RFLP-PFGE) of bacterial DNA. Results VREfm infected 26 liver recipients, 22 kidney recipients, and 9 other surgery or nephrology patients. Only five strains possessed the vanB determinant. The PFGE analysis revealed two large and several small groups of related strains. Conclusions The PFGE analysis enabled the investigation of VRE epidemiology among patients after transplantation. Strains with similar patterns most probably originated from one source and clearly suggested an outbreak. |
| Databáze: | OpenAIRE |
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