Alzheimer Disease and Its Management
| Autor: | K.P. Sampath Kumar, Barnabas Wilson, B Suresh, Malay K. Samanta, Kumaraswamy Santhi |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
medicine.medical_specialty
Degenerative Disorder Population Phenylcarbamates Rivastigmine Disease Piperidines Alzheimer Disease Memantine Prevalence medicine Animals Humans Dementia Donepezil Pharmacology (medical) Senile plaques Disease management (health) education Psychiatry Nootropic Agents Randomized Controlled Trials as Topic Pharmacology education.field_of_study Galantamine business.industry Cognition General Medicine History 20th Century medicine.disease Indans Tacrine Cholinesterase Inhibitors Alzheimer's disease business Excitatory Amino Acid Antagonists |
| Zdroj: | American Journal of Therapeutics. 13:516-526 |
| ISSN: | 1075-2765 |
| Popis: | Alzheimer disease is a progressive degenerative disorder of the brain characterized by a slow, progressive decline in cognitive function and behavior. As the disease advances, persons with Alzheimer disease have tough time with daily usage of things like using the phone, cooking, handling money, or driving the car. The disease is more common in elder population. It is estimated that Alzheimer disease affects 15 million people worldwide and approximately 4 million Americans. The clinical features of Alzheimer disease overlaps with common signs of aging, and other types of dementia, hence the diagnosis remains difficult. The neuropathologic hallmarks of the disorder are amyloid-rich senile plaques, neurofibrillary tangles, and neuronal degeneration. Drugs approved for treating Alzheimer disease include acetylcholinesterase inhibitors and N-methyl-D-aspartate (NMDA) receptor antagonist. Caregivers not getting adequate information about Alzheimer disease may believe that nothing can be done to manage its symptoms. Understanding the extent of Alzheimer disease related knowledge can assist disease management that result in improved disease management and reduced care costs. This article attempts to focus on some of the important recent developments in understanding and management of Alzheimer disease. |
| Databáze: | OpenAIRE |
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