Vesicoureteral reflux in children with suspected and proven urinary tract infection
| Autor: | Mika Venhola, Tytti Pokka, Matti Uhari, Annukka Hannula, N. P. Huttunen, Marjo Renko |
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| Rok vydání: | 2010 |
| Předmět: |
Male
Nephrology medicine.medical_specialty Urinary system Prevalence Urology Urination Urine Kidney urologic and male genital diseases Vesicoureteral reflux Internal medicine Epidemiology medicine Humans Child Ultrasonography Vesico-Ureteral Reflux business.industry medicine.disease female genital diseases and pregnancy complications Confidence interval Relative risk Urinary Tract Infections Pediatrics Perinatology and Child Health Female business |
| Zdroj: | Pediatric Nephrology. 25:1463-1469 |
| ISSN: | 1432-198X 0931-041X |
| Popis: | The aim of this study was to estimate the prevalence of vesicoureteral reflux (VUR) and clinically significant ultrasonography (US) abnormalities in a large group of children with proven and suspected urinary tract infection (UTI). The medical reports on renal US and voiding cystouretrographies (VCUG) of 2,036 children were reviewed. Renal US was performed on all children and VCUG on 1,185 children (58%). Based on the urine culture data, the UTI diagnoses were classified into five reliability classes (proven, likely, unlikely, false and no microbial data). The UTI diagnose was considered proven in 583/2036 (28.6%) and false in 145 (7.1%) cases. The prevalence of VUR was similar among those with proven and false UTI [37.4 vs. 34.8%; relative risk (RR) 1.08, 95% confidence intervals (95% CI) 0.7-1.7, P = 0.75] and decreased with increasing age (P = 0.001). Clinically significant US abnormalities occurred in 87/583 (14.9%) cases with proven UTI and significantly less often (11/145, 7.6%) in the false UTI class (RR 1.96, 95% CI 1.1-3.6, P = 0.02). Our finding supports the claim that VUR is not significantly associated to UTI and that its occurrence among children even without UTI is significantly higher than traditional estimates. This challenges the recommendations of routine VCUG after UTI. |
| Databáze: | OpenAIRE |
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