Cholangiolocarcinoma With Multiple Recurrences Successfully Treated With Repeated Liver Resection and Radiofrequency Ablation
| Autor: | Daiki Yoshii, Shinichi Akahoshi, Toru Beppu, Hideaki Miyamoto, Yoshihiko Komohara, Eri Oda, Hideaki Yuki, Kensuke Yamamura, Toshihiko Motohara, Nobutaka Sato |
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| Rok vydání: | 2020 |
| Předmět: |
Cancer Research
medicine.medical_specialty Carcinoma Hepatocellular Liver tumor Radiofrequency ablation medicine.medical_treatment Resection law.invention Cholangiocarcinoma Lesion law medicine Humans Aged Radiofrequency Ablation business.industry Liver Neoplasms Washout General Medicine medicine.disease Oncology Hepatocellular carcinoma Female Radiology Neoplasm Recurrence Local Hepatectomy medicine.symptom Stem cell business |
| Zdroj: | Anticancer Research. 40:7147-7153 |
| ISSN: | 1791-7530 0250-7005 |
| DOI: | 10.21873/anticanres.14745 |
| Popis: | Background/aim The prognosis of cholangiolocarcinoma, a rare malignant liver tumor derived from hepatic progenitor or stem cells, is considered relatively good; however, it frequently recurs. We herein present the diagnosis, histological findings, and treatment of cholangiolocarcinoma. Case report A 65-year-old woman with a large liver tumor (70 mm in diameter) was referred. Hepatocellular carcinoma was suspected based on strong early enhancement and delayed washout by enhanced computed tomography. The patient underwent curative left tri-sectionectomy. Histologically, she was diagnosed with pure cholangiolocarcinoma in a slightly fibrous liver. Three metachronous recurrent lesions (all ≤10 mm in diameter) were found between fifteen and twenty months after the initial hepatectomy. One lesion and the remaining two lesions were treated with hepatectomy and radiofrequency ablation, respectively. Two years after the initial diagnosis, she was doing well without recurrence. Conclusion Repeated hepatectomy and radiofrequency ablation might be useful for small intrahepatic recurrences of cholangiolocarcinoma. |
| Databáze: | OpenAIRE |
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