Corticospinal tract involvement in a variant of Guillain-Barré syndrome
| Autor: | Toshio Matsumoto, Itsuro Endo, Yasushi Oshima, Yoshifumi Umaki, Takao Mitsui |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Adult
Male Electrodiagnosis Adolescent Neural Conduction Pyramidal Tracts Motor nerve Hyperreflexia urologic and male genital diseases Guillain-Barre Syndrome Cerebrospinal fluid Physical Stimulation medicine Humans In patient Pleocytosis reproductive and urinary physiology Aged medicine.diagnostic_test Guillain-Barre syndrome Reflex Abnormal business.industry Upper motor neuron General Neuroscience Muscle weakness Anatomy Deep Tendon Reflex Middle Aged bacterial infections and mycoses medicine.disease Evoked Potentials Motor female genital diseases and pregnancy complications Axons medicine.anatomical_structure Neurology Anesthesia Corticospinal tract Nerve conduction study bacteria Female Neurology (clinical) medicine.symptom business Nerve conduction |
| Zdroj: | European neurology. 46(1) |
| ISSN: | 0014-3022 |
| Popis: | To determine the involvement of the corticospinal tract in Guillain-Barré syndrome (GBS), we examined central motor conduction in patients with GBS-like symptoms and hyperreflexia using a magnetic stimulation technique. The subjects were 3 patients who exhibited ascending muscle weakness 2–4 weeks after preceding infections. Deep tendon reflexes were exaggerated in all four limbs of the 3 patients. The results of cerebrospinal fluid examinations revealed protein elevation without pleocytosis. The serum anti-GM1 antibody titer was elevated in 2 patients. The results of nerve conduction study revealed axonal motor neuropathy and normal F-wave conduction. Central motor conduction time (CMCT) in patients with hyperreflexia was significantly delayed compared to that in patients with GBS and areflexia (p < 0.001), and the delayed CMCTs were significantly improved in the recovery periods (p < 0.001). Although hyperreflexia is a controversial symptom in patients with GBS, these findings indicate that there is functional corticospinal tract involvement in patients with a GBS variant. |
| Databáze: | OpenAIRE |
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