Dimerization and Anion Binding of a Fluorescent Phospholipid Analogue

Autor:	Ber Xiong, William E. Allen, Andrew L. Sargent, Ashley N. Wercholuk, Danielle M. Jessen
Rok vydání:	2012
Předmět:	Anions Fluorophore Molecular Structure Hydrogen bond Dimer Organic Chemistry Inorganic chemistry Phospholipid Fluorescence Bicarbonates chemistry.chemical_compound Crystallography chemistry Urea Phosphoric Acids Anion binding Dimerization Phospholipids Phosphocholine
Zdroj:	The Journal of Organic Chemistry. 77:6615-6619
ISSN:	1520-6904 0022-3263
DOI:	10.1021/jo3009758
Popis:	A diarylacetylene fluorophore featuring spatially separated urea and phosphocholine (PC) groups forms a macrocyclic "head-to-tail" dimer stabilized by NH(urea)···OP(PC) hydrogen bonds. At concentrations above ~2 × 10(-5) M in CH(2)Cl(2), the emission intensity of the dimer is quenched by HCO(3)(-) and H(2)PO(4)(-) but not by Cl(-) and NO(3)(-). Under more dilute conditions, all four anions are bound unselectively with association constants on the order of 10(5) M(-1).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e13fcadc92956405b772147e2fc017 https://doi.org/10.1021/jo3009758 Zobrazit plný text záznamu