Interventional radiology treatment for vascular and biliary complications following pediatric living donor liver transplantation - a retrospective study
| Autor: | Yoshiyuki Ihara, Noriki Okada, Shinya Otomo, Koichi Mizuta, Yuta Hirata, Naoya Yamada, Yukihiro Sanada, Kentraro Ushijima, Toshimi Imai, Keiko Ogaki, Takumi Katano |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Treatment outcome Portal vein Constriction Pathologic Hepatic Veins Radiology Interventional 030230 surgery 03 medical and health sciences Hepatic Artery 0302 clinical medicine Risk Factors Living Donors Humans Medicine In patient Child Vein Retrospective Studies Transplantation medicine.diagnostic_test Portal Vein business.industry Graft Survival Infant Thrombosis Interventional radiology Retrospective cohort study Liver Transplantation Surgery Treatment Outcome medicine.anatomical_structure Liver Child Preschool Female 030211 gastroenterology & hepatology business Living donor liver transplantation Artery |
| Zdroj: | Transplant International. 31 |
| ISSN: | 0934-0874 |
| DOI: | 10.1111/tri.13285 |
| Popis: | There are few long-term outcome reports for interventional radiology (IVR) treatments for vascular and biliary complications following pediatric living donor liver transplantation (LDLT). Herein, we presented our institution's experience and investigated the efficacy and issues of long-term outcome with IVR treatments. Between May 2001 and September 2016, 279 pediatric LDLTs were performed. The median age at LDLT was 1.4 years old, and the median observation period was 8.2 years. All the biliary reconstructions at LDLT were hepaticojejunostomy. The IVR treatments were selected as endovascular, radiological, or endoscopic interventions. Post-transplant hepatic vein, portal vein, hepatic artery, and biliary complications were present in 7.9%, 14.0%, 5.4%, and 18.3%, respectively. IVR treatment was the first treatment option in 81.8%, 94.9%, 46.7%, and 94.1%, respectively. The recurrence and cure rates following IVR treatment were 42.1%, 21.1%, 44.4%, and 34.0% and 84.2%, 97.4%, 100%, and 88.0%, respectively. The graft survival rates in patients with and without post-transplant vascular and biliary complications were 94.4% and 90.6%, respectively (P = 0.522). The IVR treatments for vascular and biliary complications following pediatric LDLT are the first choice option. Although the recurrence following IVR treatment is a major problem and it is necessary to carefully perform long-term follow-up, IVR treatments have good treatment outcomes. |
| Databáze: | OpenAIRE |
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