Changes in liver function after hepatic dearterialization in man
| Autor: | Kinji Ayabe, Naofumi Nagasue, Hirokuni Murakami, Sadao Arari, Izuo Kusaba, Kiichiro Ichimaru |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
Adult
Leiomyosarcoma Male medicine.medical_specialty Liver tumor Serum albumin Gastroenterology Leucyl Aminopeptidase Hepatic Artery Internal medicine medicine Cholinesterases Humans Aspartate Aminotransferases Neoplasm Metastasis Ligation Serum Albumin Aged biology medicine.diagnostic_test L-Lactate Dehydrogenase business.industry Liver Neoplasms Palliative Care Sequela Alanine Transaminase Bilirubin General Medicine Middle Aged medicine.disease Alkaline Phosphatase Surgery Isoenzymes medicine.anatomical_structure Cholesterol Liver biology.protein Alkaline phosphatase Serum Globulins Liver function business Liver function tests Artery Liver Circulation |
| Zdroj: | The Japanese journal of surgery. 3(1) |
| ISSN: | 0047-1909 |
| Popis: | With the object of palliation of hepatic malignancy, hepatic artery ligation was performed in seven patients; six with metastatic liver tumor and the one with primary liver cancer. The proper hepatic artery was ligated in five patients and the right hepatic artery in one. In another patient with metastatic leiomyosarcoma, the right and left hepatic arteries were ligated in two stages. In all patients varying degrees of clevated serum bilirubin and increased activities of serum GOT, GPT and LDH were seen in the first postoperative week which returned to preoperative levels within one to two weeks. No significant rise was found in the activities of serum alkaline phosphatase and leucine aminopeptidase, but in three patients an elevation of alkaline phosphatase was seen at a rather later period after the ligation. Serum albumin, total cholesterol, A/G ratio and cholinesterase showed gradual decreases attaining to the lowest level one to two weeks after the operation and returned to the preoperative values within three weeks. In two patients, abnormal preoperative LDH isoenzyme patterns returned to normal on the 14th postoperative day as well as total LDH activities. This study supports the view that man can tolerate an almost complete dearterialization of the liver without fatal sequela. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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