Joint-specific assessment of swelling and power Doppler in obese rheumatoid arthritis patients
| Autor: | David Elashoff, Ami Ben-Artzi, Veena K. Ranganath, John FitzGerald, Sitaram Vangala, Erin Lindsey Duffy, Erin M. Bauer |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Sports medicine Clinical Sciences Physical examination Logistic regression Autoimmune Disease Outcome measures Arthritis Rheumatoid 03 medical and health sciences 0302 clinical medicine Rheumatology Clinical Research Rheumatoid Synovitis Internal medicine Ultrasound medicine Humans Orthopedics and Sports Medicine 030212 general & internal medicine Obesity Rheumatoid arthritis Ultrasonography Nutrition Aged 030203 arthritis & rheumatology 2. Zero hunger medicine.diagnostic_test business.industry Arthritis Prevention Inflammatory and immune system Doppler Ultrasonography Doppler Middle Aged medicine.disease Orthopedics Orthopedic surgery Physical therapy Female business Body mass index Research Article |
| Zdroj: | BMC Musculoskeletal Disorders BMC musculoskeletal disorders, vol 18, iss 1 |
| ISSN: | 1471-2474 |
| Popis: | Background Clinical swollen joint examination of the obese rheumatoid arthritis (RA) patient can be difficult. Musculoskeletal Ultrasound (MSUS) has higher sensitivity than physical examination for swollen joints (SJ). The purpose of this study was to determine the joint-specific association between power Doppler (PDUS) and clinical SJ in RA across body mass index (BMI) categories. Methods Cross-sectional clinical and laboratory data were collected on 43 RA patients. PDUS was performed on 9 joints (wrist, metacarpalphalangeal 2–5, proximal interphalgeal 2/3 and metatarsalphalangeal 2/5). DAS28 and clinical disease activity index (CDAI) were calculated. Patients were categorized by BMI: 30. Demographic and clinical characteristics were compared across BMI groups with Kruskal-Wallis test and chi-square tests. Joint-level associations between PDUS and clinically SJ were evaluated with mixed effects logistic regression models. Results While demographics and clinically-determined disease activity were similar among BMI groups, PDUS scores significantly differed (p = 0.02). Using PDUS activity as the reference standard for synovitis and clinically SJ as the test, the positive predictive value of SJ was significantly lower in higher BMI groups (0.71 in BMI |
| Databáze: | OpenAIRE |
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