Acute disseminated encephalomyelitis in two renal transplant patients: is there a role for Epstein-Barr virus reactivation?
| Autor: | L. Daelman, S Lavaud, Ayman Tourbah, O Toupance, Nathalie Caucheteux, Adil Maarouf |
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| Rok vydání: | 2013 |
| Předmět: |
Male
Epstein-Barr Virus Infections Herpesvirus 4 Human Pathology medicine.medical_specialty medicine.disease_cause Virus Immunocompromised Host medicine Humans Immunodeficiency business.industry Multiple sclerosis Encephalomyelitis Acute Disseminated Middle Aged medicine.disease Kidney Transplantation Magnetic Resonance Imaging Epstein–Barr virus Pathophysiology Transplantation Neurology Infectious disease (medical specialty) Immunology Acute disseminated encephalomyelitis Female Virus Activation Neurology (clinical) business |
| Zdroj: | Multiple Sclerosis Journal. 19:1222-1225 |
| ISSN: | 1477-0970 1352-4585 |
| DOI: | 10.1177/1352458513478674 |
| Popis: | Acute disseminated encephalomyelitis (ADEM) is a rare inflammatory demyelinating disease of the central nervous system, usually occurring after a vaccination or infectious disease. It has been exceptionally described in transplanted patients. The pathophysiology remains incompletely understood. We report the clinical, biological and magnetic resonance imaging (MRI) presentation and evolution of two kidney-transplanted patients with ADEM associated with local Epstein-Barr virus (EBV) reactivation. ADEM may occur in transplanted patients with favorable evolution. Its pathophysiology is uncertain, and the implication of EBV is discussed. |
| Databáze: | OpenAIRE |
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