Anterior segment mechanisms of protection during herpes simplex virus 1 infection
| Autor: | Heather M. Cathcart, Sally S. Atherton |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Stromal keratitis
viruses Herpesvirus 1 Human HSL and HSV Biology medicine.disease_cause Article Keratitis Interferon-gamma Corneal blindness Stroma Anterior Eye Segment medicine Animals Humans Microglia Retinal Necrosis Syndrome Acute General Medicine medicine.disease Virology eye diseases Ophthalmology Herpes simplex virus medicine.anatomical_structure Immunology Keratitis Herpetic sense organs Acute retinal necrosis |
| Zdroj: | Japanese Journal of Ophthalmology |
| ISSN: | 1613-2246 0021-5155 |
| DOI: | 10.1007/s10384-010-0798-9 |
| Popis: | Herpes simplex viruses (HSV) are linear double stranded DNA viruses that are highly disseminated in nature and characterized by lifetime latency in their host 1. They are also a leading cause of infectious corneal blindness in the United States 2 and a major cause of corneal opacity worldwide. One example is HSV-1 which causes herpes stromal keratitis (HSK), an infection of the corneal stroma which, if not appropriately treated, may result in vascularization and scarring that may eventually lead to blindness 3. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink