Linear and nonlinear heart rate dynamics in elderly inpatients. Relations with comorbidity and depression
| Autor: | Emilio Yangüez, Ignacio Martínez-Navarro, Pere Llorens-Soriano, Cristina Blasco-Lafarga, María Elisa Sisamón, Nuria Caus |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Adult
Male medicine.medical_specialty Heart Diseases Population Context (language use) Risk Assessment elderly Sampling Studies inpatients Electrocardiography Sex Factors Heart Rate Internal medicine Heart rate Prevalence medicine Animals Humans Heart rate variability education Geriatric Assessment Depression (differential diagnoses) Aged Aged 80 and over education.field_of_study business.industry Age Factors heart rate variability General Medicine medicine.disease Comorbidity Sample entropy comorbidity Nonlinear Dynamics Data Interpretation Statistical depression Physical therapy Female Geriatric Depression Scale business |
| Zdroj: | Medicina Volume 46 Issue 6 Medicina; Volume 46; Issue 6; Pages: 393 |
| ISSN: | 1010-660X |
| DOI: | 10.3390/medicina46060055 |
| Popis: | Background. Hospitalization processes are known to increase depressive symptoms arising among elderly population. Meanwhile, dysregulation of cardiac autonomic function has been suggested to link depression and cardiovascular mortality. In this context, analysis of heart rate variability (HRV) is emerging as a powerful mortality risk stratifier clinical tool. The purpose of the study was to examine the relationship among HRV, depression, and comorbidity risk among an elderly inpatient population. Material and methods. Twenty-six subjects (aged 78±9 years) were recruited from the Short- Term Stay Unit at the Hospital General de Alicante. Before joining a Physical Activity Program aimed to prevent functional impairment and after medical selection and written consent, inpatients were tested for heart rate variability, Yesavage Geriatric Depression Scale, and Charlson comorbidity index score. Results. Men compared to women showed a signifi cantly larger CCI score. Short-term scaling exponent (α1), derived from detrended fl uctuation analysis, showed a negative correlation with Charlson comorbidity index. Conversely, a positive correlation was found between sample entropy (SampEn) and Yesavage Scale. Conclusions. On the one hand, fractal analysis of HRV confirms to be useful as a risk stratifier tool. On the other hand, SampEn is proposed to be reflecting a non-neurally generated complexity when accompanied with low values of α1. Accordingly, in this regime, it would be indicative of a paradoxical gradual reduction in cardiac autonomic control, accentuated with the severity of depressive symptoms. |
| Databáze: | OpenAIRE |
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