Comparison of the Effects of Azelastine and Fluticasone Nasal Sprays in the Treatment of Allergic Rhinitis

Autor: Dhanya Krishnakumar, Bini Faizal, Anjaly S. Nair
Rok vydání: 2021
Předmět:
Zdroj: Indian Journal of Otolaryngology and Head & Neck Surgery. 74:1632-1637
ISSN: 0973-7707
2231-3796
DOI: 10.1007/s12070-021-02686-7
Popis: Allergic rhinitis is a highly prevalent, allergen-induced disease. Intranasal corticosteroids are currently the first-line therapy for these patients. It is uncertain whether intranasal antihistamines have comparable efficacy. This study compares effects of Azelastine and Fluticasone nasal spray in patients with allergic rhinitis. Prospective comparative study including 240 patients with allergic rhinitis was conducted with 120 each in fluticasone and azelastine group. Nasal sprays were given for period of three months along with an oral antihistamine. Follow up was done after three months. Pre and post treatment symptom assessment were done using Total nasal symptom score. The median TNSS in pre and post treatment of group A (fluticasone) is 10(4) and 1(3) which shows statistical significance with p value
Databáze: OpenAIRE