Intragastric infusion of pea-protein hydrolysate reduces test-meal size in rats more than pea protein
| Autor: | Maria C Tasker, Martin Foltz, Wolfgang Langhans, Margriet Westerterp, Doreen Häberer, Nori Geary |
|---|---|
| Přispěvatelé: | Humane Biologie, RS: NUTRIM - R1 - Metabolic Syndrome |
| Rok vydání: | 2010 |
| Předmět: |
Glucagon-like peptide-1
Male medicine.medical_specialty Time Factors Adult male Protein Hydrolysates medicine.medical_treatment WEIGHT-LOSS Experimental and Cognitive Psychology Vagotomy TERM FOOD-INTAKE Hydrolysate Rats Sprague-Dawley Behavioral Neuroscience GLUTAMATE Eating Weight loss Food intake Glucagon-Like Peptide 1 Internal medicine Parasympathectomy medicine Animals Insulin SATIETY Cholecystokinin AMINO-ACID PROFILES Test meal PLASMA Chemistry Pea protein Drug Administration Routes digestive oral and skin physiology Vagus CHOLECYSTOKININ Peas Proteins Vagus Nerve Feeding Behavior Glucagon DIETARY PROTEINS Rats Endocrinology FAT Area Under Curve HIGH-CARBOHYDRATE medicine.symptom |
| Zdroj: | Physiology & Behavior, 104(5), 1041-1047. Elsevier Science |
| ISSN: | 1873-507X 0031-9384 |
| Popis: | Because protein hydrolysates are digested faster than the corresponding proteins, they may increase or hasten the acute eating-inhibitory effect of protein. Potential mediating mechanisms include accelerated or greater release of satiating gut peptides and activation of metabolic signals that inhibit eating. We tested these hypotheses in adult male rats that were surgically equipped with intragastric (IG) cannulas and adapted to 30-min test meals at dark onset after 14-h food deprivation. Equiosmotic 12 ml loads of saline-urea control (C), 13.6% pea protein (PP), or 13.6% PP hydrolysate (PPH, DSM/DFS, Delft, The Netherlands) solutions were IC infused in 1 min just before test meals. PPH reduced test-meal size compared to C more than PP (-3.8 +/- 0.3 g vs. 2.6 +/- 0.4 g: P |
| Databáze: | OpenAIRE |
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