Impact of maternal HIV infection on obstetrical and early neonatal outcome
| Autor: | Thomas C. Quinn, J. Embree, Hunnington Pamba, King K. Holmes, Pacita L. Roberts, Gregory Maitha, Francis A. Plummer, Peter Piot, M Braddick, G. Vercauteren, Jack O. Ndinya-Achola, Michael W Adler, Joan K. Kreiss, P. Datta |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Male Sexual partner Pediatrics medicine.medical_specialty Birth weight Immunology Population Gestational Age HIV Infections Congenital Abnormalities Pregnancy Risk Factors medicine Birth Weight Humans Immunology and Allergy Pregnancy Complications Infectious education Fetal Death education.field_of_study business.industry Infant Newborn Pregnancy Outcome Gestational age Odds ratio Infant Low Birth Weight medicine.disease Kenya Low birth weight Infectious Diseases Case-Control Studies Female Apgar score medicine.symptom business |
| Zdroj: | AIDS. 4:1001-1006 |
| ISSN: | 0269-9370 |
| DOI: | 10.1097/00002030-199010000-00009 |
| Popis: | In a case-control study of 177 HIV-seropositive and 326 seronegative women and their newborns in Nairobi, Kenya, maternal HIV infection at term was independently associated with travel to other African countries [odds ratio (OR) 4.9, P less than 0.0001], history of a blood transfusion since 1980 (OR 3.5, P = 0.01), history of more than one sexual partner in the previous 5 years (OR 1.8, P = 0.02) and unmarried status (OR 1.8, P = 0.02). Neonates of HIV-positive and HIV-negative women differed little with respect to occurrence of congenital malformations, stillbirths, in-hospital mortality, sex, APGAR score, or gestational age. However, the mean birth weight of singleton neonates of HIV-positive women was significantly lower than that of controls (3090 versus 3220 g, P = 0.005), and birth weight was less than 2500 g in 9% of cases and 3% of controls (OR 3.0, P = 0.007). Among neonates of HIV-seropositive women, birth weight was less than 2500 g in 17% if mothers were symptomatic and 6% if mothers were asymptomatic (OR 3.4, P = 0.08). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|