Surveillance of Immunosuppression During Pregnancy After Heart Transplantation: Case Report
| Autor: | Nai-Kuan Chou, Yih-Sharng Chen, Hsi-Yu Yu, C.-I. Tsao, Nai-Hsin Chi, Shoei-Shen Wang, Szu-Fen Huang, C.-Y. Tsan, Chih-Hsien Wang, Chia-Tung Shun, I-Hui Wu |
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| Rok vydání: | 2015 |
| Předmět: |
Blood level
Adult Graft Rejection Pediatrics medicine.medical_specialty medicine.medical_treatment Pregnancy Complications Cardiovascular MEDLINE 030230 surgery 010501 environmental sciences 01 natural sciences 03 medical and health sciences 0302 clinical medicine Pregnancy Blood drug medicine Humans Intensive care medicine 0105 earth and related environmental sciences Heart transplantation Immunosuppression Therapy Transplantation business.industry Infant Newborn Pregnancy Outcome Immunosuppression University hospital medicine.disease Heart Transplantation Surgery Female business Immunosuppressive Agents |
| Zdroj: | Transplantation proceedings. 48(3) |
| ISSN: | 1873-2623 |
| Popis: | Background Transplantation and immunosuppressive drugs are major limitations to the success of pregnancy. In 1988, the first pregnancy after a heart transplant was reported, which has given female recipients the hope to give birth. During pregnancy, physiologic changes with increased blood volume and hemodilution may influence blood drug level. Case Report We reported our experience in monitoring on immunosuppressive drugs for 2 cases. Both of them underwent heart transplantation in 2006 and were 34 and 37 years old at time of pregnancy. For both cases, we frequently monitored the blood level and increased the dosage of immunosuppressive drugs accordingly. Both cases had uneventful pregnancy and delivery to healthy babies at the National Taiwan University Hospital in Taiwan. Their postpartum courses were uneventful as well. Conclusions We advocate adjusting the immunosuppressive dosage according to the blood level before pregnancy. |
| Databáze: | OpenAIRE |
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