Comparative efficacy and safety investigation of eight antidiabetic herbal products distributed within South- Western Nigeria

Autor: Adegbolagun, Olayemi Modupe, Ibukun, Olaoluwa Daniel, Ogunremi, Yetunde
Rok vydání: 2023
Předmět:
Zdroj: Journal of Pharmacy & Bioresources; Vol. 20 No. 1 (2023); 1-13
ISSN: 0189-8442
Popis: Herbal preparations, often promoted as being natural and completely safe, are gaining popularity in the management of diabetes mellitus, despite lack of scientific data to confirm their efficacy and safety claims. This study investigated efficacy and safety of eight commercial antidiabetic herbal products. Antidiabetic activities were investigated in streptozotocin-induced diabetic rats at doses based on their labelled recommended dosages using metformin as reference drug. Body weights, blood glucose level (BGL), haematogical and biochemical parameters as well as histopathology of the kidney and lungs were assessed by standard procedures. All the samples demonstrated weight reduction (p
Databáze: OpenAIRE