The effect of an intramedullary self-reinforced poly-L-lactide (SR-PLLA) implant on growing bone with special reference to fixation properties. An experimental study on growing rabbits
| Autor: | E. Antero Mäkelä, Hannu Miettinen, Jyrki Vainio, Pertti Törmälä, Pentti Rokkanen |
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| Rok vydání: | 1992 |
| Předmět: |
medicine.medical_specialty
Materials science Polyesters medicine.medical_treatment Biomedical Engineering Biophysics Bioengineering Osteotomy Bone and Bones law.invention Biomaterials Intramedullary rod chemistry.chemical_compound Fixation (surgical) Polylactic acid law Poly-L-lactide medicine Animals Femur Reduction (orthopedic surgery) Bone growth Bone Development Tibia Prostheses and Implants Internal Fixators Surgery Radiography chemistry Rabbits Implant Biomedical engineering |
| Zdroj: | Journal of Biomaterials Science, Polymer Edition. 3:443-450 |
| ISSN: | 1568-5624 0920-5063 |
| DOI: | 10.1163/156856292x00420 |
| Popis: | Polylactic acid (PLA) is a synthetic biodegradable material. The self-reinforced implants made of poly-L-lactic acid (SR-PLLA) were manufactured of biodegradable polymeric matrix reinforced with fibres of the same material. The purpose of this study was to find out the effect of an intramedullary SR-PLLA implant on growing bone and its applicability to the fixation of a femoral shaft osteotomy in a growing rabbit. In seven rabbits 6 weeks of age a SR-PLLA implant 2.0 mm in diameter and 50 mm in length was introduced into the intramedullary cavity of the right femur. A proximal femoral shaft osteotomy of the right femur was made in another ten 6-weeks-old rabbits. After accurate reduction, fixation of the osteotomy was achieved with an intramedullary 2.0 mm by 50 mm SR-PLLA-rod. The follow-up times were 6 and 28 weeks. An intramedullary SR-PLLA-rod neither caused any disturbance of the bone growth nor abnormalities of the peripheral blood cell counts. Solid union of the osteotomy was seen in six weeks after fixation with SR-PLLA implant. |
| Databáze: | OpenAIRE |
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