Supplementary Figure 1-6 from HMDB and 5-AzadC Combination Reverses Tumor Suppressor CCAAT/Enhancer-Binding Protein Delta to Strengthen the Death of Liver Cancer Cells

Autor: Ju-Ming Wang, Wan-Chen Wu, Chiou-Hwa Yuh, Hong-Yue Lai, Chia-Jui Yen, Yen-Chun Pan, Chiung-Yuan Ko, Hsin-Hwa Tsai, Chien-Feng Li
Rok vydání: 2023
DOI: 10.1158/1535-7163.22501701
Popis: Supplemental Figure 1. Anti-cancer drugs induce CEBPD expression in liver cancer cells. Supplemental Figure 2. Scheme of depression of epigenetic effects to enhance HMDB-induced CEBPD expression and apoptosis. Supplemental Figure 3. (Related to Figure 5) The p38/CREB pathway mediates HMDB-induced CEBPD transcriptional activation and CEBPD participates in HMDB-induced apoptosis in liver cancer cells. Supplemental Figure 4. (Related to Figure 5) Combinatorial treatment of HMDB and 5-AzadC can additively affect cell death. Supplemental Figure 5. (Related to Figure 5) Enhanced cytotoxic effects of HMDB combined with 5-AzadC on Huh7 and HepG2 cells. Supplemental Figure 6. (Related to Figure 5) Loss of CEBPD attenuated dual treatment-induced tumor killing in liver cancer cells.
Databáze: OpenAIRE