Economic health care costs of blood culture contamination: A systematic review
| Autor: | Kenneth L. Muldrew, Erik Skoglund, Kevin W. Garey, Casey J. Dempsey |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Epidemiology Pharmacy Gram-Positive Bacteria 03 medical and health sciences 0302 clinical medicine Economic cost Health care medicine Humans Infection control Antimicrobial stewardship Blood culture 030212 general & internal medicine 0303 health sciences medicine.diagnostic_test 030306 microbiology business.industry Health Policy Public Health Environmental and Occupational Health Health Care Costs Contamination Infectious Diseases Systematic review Blood Culture Emergency medicine Equipment Contamination Health Expenditures business |
| Zdroj: | American Journal of Infection Control. 47:963-967 |
| ISSN: | 0196-6553 |
| DOI: | 10.1016/j.ajic.2018.12.020 |
| Popis: | Background Blood culture contamination with gram-positive organisms is a common occurrence in patients suspected of bloodstream infections, especially in emergency departments. Although numerous research studies have investigated the cost implications of blood culture contamination, a contemporary systematic review of the literature has not been performed. The aim of this project was to perform a systematic review of the published literature on the economic costs of blood culture contamination. Methods PubMed was searched (January 1, 1978, to July 15, 2018) using the search terms “blood culture contamination” or “false-positive blood cultures.” Articles were title searched and abstracts were reviewed for eligible articles that reported immediate or downstream economic costs of blood culture contamination. Results and Discussion The PubMed search identified 151 relevant articles by title search, with 49 articles included after abstract review. From the studies included, overall blood culture contamination rates ranged from 0.9%-41%. Up to 59% of patients received unnecessary treatment with parenteral vancomycin as a result of blood culture contamination, resulting in increased pharmacy charges between $210 and $12,611 per patient. Increases in total laboratory charges between $2,397 and $11,152 per patient were reported. Attributable hospital length of stay increases due to blood culture contamination ranged from 1-22 days. Conclusions This systematic review of the literature identified several areas of health care expenditure associated with blood culture contamination. Interventions to reduce the risk of blood culture contamination would avoid downstream economic costs. |
| Databáze: | OpenAIRE |
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