Malnutrition According to GLIM Criteria Is Associated with Mortality and Hospitalizations in Rehabilitation Patients with Stable Chronic Obstructive Pulmonary Disease
| Autor: | Vanesa Dávalos-Yerovi, Dolores Sánchez-Rodríguez, Elena Muñoz, Ester Marco, Delky Meza-Valderrama, Marta Tejero-Sánchez, Diego A. Rodríguez, Xavier Duran, Maria Dolors Muns, Anna Guillén-Solà, Esther Duarte |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Male
0301 basic medicine medicine.medical_specialty Multivariate analysis medicine.medical_treatment GLIM lcsh:TX341-641 malnutrition Article Body Mass Index rehabilitation Pulmonary Disease Chronic Obstructive 03 medical and health sciences 0302 clinical medicine Weight loss Internal medicine Weight Loss Prevalence medicine Humans Pulmonary rehabilitation Prospective Studies 030212 general & internal medicine Mortality chronic pulmonary obstructive disease Prospective cohort study Aged COPD 030109 nutrition & dietetics Nutrition and Dietetics Proportional hazards model business.industry Malnutrition Rehabilitation Middle Aged medicine.disease mortality Hospitalization Leadership Multivariate Analysis Female Chronic pulmonary obstructive disease medicine.symptom business lcsh:Nutrition. Foods and food supply hospitalization Food Science |
| Zdroj: | Nutrients, Vol 13, Iss 369, p 369 (2021) Nutrients Volume 13 Issue 2 Elena Muñoz-Redondo |
| ISSN: | 2072-6643 |
| DOI: | 10.3390/nu13020369 |
| Popis: | Malnutrition has a negative impact on patients with chronic pulmonary obstructive disease (COPD). The purpose of this study was to assess the prevalence of malnutrition, defined by the Global Leadership Initiative for Malnutrition (GLIM), in stable COPD patients referred to pulmonary rehabilitation, and to explore potential associations of malnutrition according to GLIM, and its components, with increased risk of mortality and hospitalizations in 2 years. In a post-hoc analysis of a prospective cohort of 200 rehabilitation patients with stable COPD, main outcome variables were hospital admissions, length of stay, and mortality during a 2-year follow-up. Covariates were malnutrition according to GLIM and its phenotypic criteria: unintentional weight loss, low body mass index (BMI), and low fat-free mass (FFM). Univariate and multivariate analysis were performed using logistic and proportional hazard Cox regression. Malnutrition according to GLIM showed 45% prevalence and was associated with increased mortality risk. Low age-related BMI and FFM were independently associated with mortality, which persisted after adjustment for age and lung function. Malnutrition and low BMI were also associated with increased risk of hospitalization. Malnutrition according to GLIM criteria was highly prevalent in rehabilitation patients with COPD and was associated with nearly 3 times greater mortality and hospitalization risk. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|