Integrated Framework for Identifying Toxic Transformation Products in Complex Environmental Mixtures
| Autor: | Eunha Hoh, Ivan A. Titaley, Leah Chibwe, Staci L. Massey Simonich |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
Engineering
Ecology business.industry Health Toxicology and Mutagenesis 010401 analytical chemistry Nanotechnology 010501 environmental sciences 01 natural sciences Pollution Article 0104 chemical sciences Screening analysis Environmental Chemistry Biochemical engineering business Waste Management and Disposal 0105 earth and related environmental sciences Water Science and Technology |
| Zdroj: | Environ Sci Technol Lett |
| ISSN: | 2328-8930 |
| Popis: | Complex environmental mixtures consist of hundreds to thousands of unknown and unregulated organic compounds that may have toxicological relevance, including transformation products (TPs) of anthropogenic organic pollutants. Non-targeted analysis and suspect screening analysis offer analytical approaches for potentially identifying these toxic transformation products. However, additional tools and strategies are needed in order to reduce the number of chemicals of interest and focus analytical efforts on chemicals that may pose risks to humans and the environment. This brief review highlights recent developments in this field and suggests an integrated framework that incorporates complementary instrumental techniques, computational chemistry, and toxicity analysis, for prioritizing and identifying toxic TPs in the environment. |
| Databáze: | OpenAIRE |
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