Glycerol interference in serum lipase assay falsely indicates pancreas injury
| Autor: | Fred S. Apple, Lynne M. Preese, Laura Bilodeau, Dwight A. Grotte |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Adult
Glycerol medicine.medical_specialty Pancreatic disease Triacylglycerol lipase chemistry.chemical_compound Internal medicine medicine Humans False Positive Reactions Lipase Hepatology biology business.industry Gastroenterology medicine.disease Endocrinology Pancreatitis chemistry Acute Disease Toxicity biology.protein Female Reagent Kits Diagnostic Differential diagnosis Pancreatic injury business |
| Zdroj: | Gastroenterology. 103:1066-1067 |
| ISSN: | 0016-5085 |
| DOI: | 10.1016/0016-5085(92)90044-y |
| Popis: | The measurement of serum lipase activity has been shown to be a very sensitive and specific marker for the diagnosis of pancreatic injury. Two case reports are presented showing that glycerol ingested coincidentally in the formulation of several medications taken therapeutically and given in the emergency room causes a falsely elevated serum lipase activity when measured on the Kodak Ektachem 700 clinical analyzer (Eastman Kodak Co., Rochester, NY). The transient but falsely elevated serum lipase activity could potentially affect the differential diagnosis of patients by the admitting physician. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|