Clinical Phenotype and Contagiousness of Early Breakthrough SARS-CoV-2 Infections after BNT162b2 COVID-19 mRNA Vaccine: A Parallel Cohort Study in Healthcare Workers
Autor: | Federica Verga, Giovanni Di Perri, Valeria Ghisetti, Elisa Burdino, Stefano Bonora, Andrea Calcagno, Teresa Emanuele, Mattia Trunfio |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19) Vaccination schedule Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Immunology Asymptomatic Article cycle threshold COVID-19 vaccine contagiousness symptoms protection clinical manifestations mRNA vaccines BNT162b2 Internal medicine Drug Discovery Medicine Pharmacology (medical) Pharmacology Cycle threshold business.industry Clinical manifestations Contagiousness MRNA vaccines Protection Symptoms Vaccine Vaccination Infectious Diseases Relative risk medicine.symptom business Cohort study |
Zdroj: | Vaccines, Vol 9, Iss 1377, p 1377 (2021) Vaccines Vaccines; Volume 9; Issue 12; Pages: 1377 |
ISSN: | 2076-393X |
DOI: | 10.3390/vaccines9121377 |
Popis: | We evaluated the clinical protection of BNT162b2 mRNA vaccine in healthcare workers (HCWs) and how COVID-19 manifestations and contagiousness change as the time since first dose increases. A matched (1:2 ratio) parallel cohort study was performed. During the first three months of vaccination campaign, HCWs of the entire health district ASL Città di Torino (Turin, Italy) were classified according to SARS-CoV-2-positivity in respect of the vaccination schedule: post-first-dose (fHCWs |
Databáze: | OpenAIRE |
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