Correlation between Clinical Characteristics and Chest Computed Tomography Findings of Pulmonary Cryptococcosis
| Autor: | Emiri Baba, Masami Yabe, Kazuyoshi Kuwano, Masamichi Takagi, Masahiro Yoshida, Keitaro Okuda, Shota Fujimoto, Hideaki Yamakawa, Takeo Ishikawa, Hiroaki Katagi |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine medicine.medical_specialty Anemia Computed tomography Review Article Asymptomatic medicine Humans Aged Retrospective Studies lcsh:RC705-779 Aged 80 and over Pulmonary cryptococcosis Lung Lung Diseases Fungal medicine.diagnostic_test business.industry Medical record Retrospective cohort study lcsh:Diseases of the respiratory system Cryptococcosis General Medicine Middle Aged medicine.disease medicine.anatomical_structure Female Radiology medicine.symptom Tomography X-Ray Computed business |
| Zdroj: | Pulmonary Medicine Pulmonary Medicine, Vol 2015 (2015) |
| ISSN: | 2090-1844 2090-1836 |
| DOI: | 10.1155/2015/703407 |
| Popis: | Objective. The aim of this study was to review HIV-negative patients with pulmonary cryptococcosis to analyze the correlations between clinical characteristics and chest computed tomography (CT) findings.Methods. We retrospectively analyzed medical records of 16 HIV-negative patients with pulmonary cryptococcosis diagnosed at our institution, and clinical characteristics of the patients with nodules or masses without ground-glass attenuation (GGA)/consolidation type were compared with those of patients with inclusive GGA or consolidation type.Results. Host status was immunocompromised (81.2%) in most of the patients, and 6 (37.5%) were asymptomatic. The most frequent radiologic abnormalities on chest CT scans were one or more nodules (87.5%), GGA (37.5%), and consolidations (18.8%). Most lesions were located in the lower lung. Levels of hemoglobin and platelets were significantly lower in patients with inclusive GGA or consolidation type. Although the differences were not significant, patients with inclusive GGA or consolidation type tended to have a C-reactive protein level of ≥1.0 mg/dL.Conclusion. If a patient with anemia and thrombocytopenia shows GGA or consolidation in the lung, pulmonary cryptococcosis should be given careful consideration. |
| Databáze: | OpenAIRE |
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