Visual Performance as a Function of Luminance in Glaucoma
| Autor: | Nomdo M. Jansonius, Marije H. de Boer, Ronald A. J. M. Bierings |
|---|---|
| Přispěvatelé: | Perceptual and Cognitive Neuroscience (PCN) |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
Visual acuity Light genetic structures flicker sensitivity Visual Acuity Glaucoma Luminance Flicker Fusion 0302 clinical medicine perimetry Foveal psychophysics QUALITY-OF-LIFE Psychophysics ADAPTATION ABNORMALITIES SPATIAL SUMMATION MODULATION SENSITIVITY Mathematics Aged 80 and over 05 social sciences Middle Aged dark adaptation Visual field LIGHT ADAPTATION PARVOCELLULAR PATHWAYS Female medicine.symptom OPEN-ANGLE GLAUCOMA Glaucoma Open-Angle Adult Open angle glaucoma Flicker fusion threshold Retina 050105 experimental psychology COLLABORATIVE INITIAL GLAUCOMA 03 medical and health sciences CONTRAST SENSITIVITY medicine Humans 0501 psychology and cognitive sciences Aged FLICKER PERIMETRY medicine.disease eye diseases glaucoma Case-Control Studies Law 030221 ophthalmology & optometry Visual Field Tests sense organs Visual Fields |
| Zdroj: | Investigative ophthalmology & visual science, 59(8), 3416-3423. ASSOC RESEARCH VISION OPHTHALMOLOGY INC |
| ISSN: | 0146-0404 |
| DOI: | 10.1167/iovs.17-22497 |
| Popis: | PURPOSE. To determine whether the De Vries-Rose, Weber's, and Ferry-Porter's law, which describe visual performance as a function of luminance, also hold in patients with glaucoma.METHODS. A case-control study with 19 glaucoma patients and 45 controls, all with normal visual acuity. We measured foveal and peripheral contrast sensitivity (CS) using static perimetry and foveal and peripheral critical fusion frequency (CFF; stimulus diameter 1 degrees) as a function of luminance (0.02 to 200 cd/m(2)). ANOVA was used to analyze the effect of glaucoma and luminance on CS and CFF; analyses were adjusted for age and sex.RESULTS. Foveally, logCS was proportional to log luminance at lower luminances (de Vries-Rose) and saturated at higher luminances (Weber); glaucoma patients had a 0.4 log unit lower logCS than controls (P CONCLUSIONS. Even in apparently intact areas of the visual field, visual performance is worse in glaucoma patients than in healthy subjects for a wide range of luminances, without a clear luminance dependency that is consistent across the various experiments. This indicates impaired signal processing downstream in the retina and beyond, rather than an impaired light adaptation in the strictest sense. |
| Databáze: | OpenAIRE |
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